Kukonzekera kwa procaine & procaine hcl

Procaine maziko

CAS: 59-46-1

Maonekedwe: ufa woyera wa crystalline

Malo osungunuka (malo otentha): 59 ~ 62 ℃

Fomula ya maselo: c13h2on2o2

Kulemera kwa molekyulu: 236.31

Procaine hcl

CAS: 51-05-8

Mu botolo la 250ml la makosi atatu lokhala ndi chotsitsimutsa ndi thermometer, madzi a nitrocaine okhala ndi pH ya 4.0-4.2 amawonjezeredwa.Pakugwedezeka kwathunthu, ufa wachitsulo wophatikizidwa umawonjezeredwa pa 25 ℃ kangapo.Pambuyo powonjezera, kutentha kwazomwe zimatuluka kumangobwera ndikusunga 40-45 ℃.Nthawi yake inali 2 hours.Pambuyo kusefera, zotsalira za fyuluta zimatsukidwa kawiri ndi madzi pang'ono, njira yotsuka imaphatikizidwa ndi filtrate, acidified to pH 5 ndi dilute hydrochloric acid (10%), ndi saturated sodium sulfide solution imawonjezeredwa ku pH 7.8- 8.0 kuti muchepetse mchere wachitsulo munjira yothetsera.The filtrate ndi acidified kuti ph6 ndi pang'ono kuchepetsa hydrochloric acid, ndiyeno usavutike mtima pa 50-60 ℃ kwa mphindi 10 ndi pang'ono adamulowetsa mpweya.Zotsalira za fyuluta zimatsukidwa kamodzi ndi madzi pang'ono, njira yotsuka imaphatikizidwa ndi filtrate, itakhazikika mpaka pansi pa 10 ℃, ndi alkalized ndi 20% NaOH mpaka procaine itasiyanitsidwa kwathunthu (pH 9.5-10.5).Sefa, sambani kawiri, kanikizani ndikukhetsa kuti mupange mchere (procaine hcl)