Kuyambira chaka cha 2007, ndife amodzi otsogolaufa wa orlistatwopanga katundu ku china
Orlistat (CAS NO.96829-58-2) ndi mankhwala opangidwa kuti athetse kunenepa kwambiri.Amagwiritsidwa ntchito makamaka poletsa kuyamwa kwamafuta m'zakudya za anthu, potero amachepetsa kudya kwa caloric.Kupatula apo, idapangidwa kuti igwiritsidwe ntchito limodzi ndi zakudya zoyang'aniridwa ndi dokotala.
| Kanthu | Zofunikira | Zotsatira za mayeso |
| Maonekedwe | panthawi yopuma-pamene ufa | White ufa |
| Chizindikiritso | HPLC nthawi yosungira | Zimagwirizana |
| Melting Point | 42 ºC -45°C | 42°C-44°C |
| Kuzungulira kwapadera kwa kuwala | -31.0°~-41.0° | -36.0 ° |
| Purity ndi HPLC | osachepera 98.0% | 98.5% |
| Chidetso chonse | osapitirira 2.0% | 1.6% |
| Kusadetsedwa kwakukulu kwamunthu payekha | osapitirira 0.5% | 0.3% |
| Zomwe zili m'madzi%(K&F) | osapitirira 0.5% | 0.1% |
| Zotsalira zosungunulira | EtOH osapitirira 0.5% | ND |
| EtAC osapitirira 0.5% | ND | |
| n-Heptane osapitirira 0.5% | zosakwana 0.1% | |
| Zotsalira pakuyatsa | zosakwana 0.2% | 0.10% |
| Zitsulo zolemera ngati Pb | osapitirira 20ppm | zosakwana 20ppm |
| Kuyesa (HPLC) | osachepera 98.0% | 99.60% |
| Mapeto | Imakwaniritsa Zofunikira | |
Orlistat ndi mtundu watsopano wodziwika padziko lonse wamankhwala ochepetsa thupi.Dzina lake lamalonda ndi Sainike ndipo linayamba kugulitsidwa ku New Zealand mu 1998. Orlistat ndi nthawi yayitali komanso yothandiza kwambiri ya m'mimba ya lipase inhibitor, ndipo imakhala yosasungunuka m'madzi, imasungunuka mu chloroform, ndipo imasungunuka mosavuta mu ethanol.
Orlistat ikhoza kugwiritsidwa ntchito kuchipatala pochiza kunenepa kwambiri.Nthawi zambiri, mlingo wa 120mg umatengedwa katatu patsiku mkati mwa ola limodzi la chakudya.Kuonda kumayamba kuchitika pakatha milungu iwiri yogwiritsa ntchito.Ikhoza kugwiritsidwa ntchito mosalekeza kwa miyezi 6-12, ndipo zotsatira zake zidzasiya kuwonjezeka pambuyo pa mlingo wa tsiku ndi tsiku upambana 400mg.Mankhwalawa ndi oyenera kugwiritsidwa ntchito limodzi ndi zakudya zochepa zama calorie ndi anthu onenepa komanso onenepa kwambiri, komanso angagwiritsidwe ntchito ngati chithandizo chanthawi yayitali kwa odwala omwe akumana ndi zovuta zokhudzana ndi kulemera.Orlistat ili ndi mphamvu yoletsa kulemera kwanthawi yayitali yomwe imachepetsa ndikusunga kulemera ndikuletsa kuyambiranso.Kugwiritsa ntchito Orlistat kumatha kuchepetsa zomwe zimachitika chifukwa cha kulemera ndi matenda, kuphatikizapo hypercholesterolemia, matenda a shuga a mtundu wa 2, kulolerana kwa shuga, hyperinsulinemia, ndi matenda oopsa, ndipo zimatha kuchepetsa mafuta m'ziwalo.Orlistat imasinthanso kuchuluka kwa lipids m'magazi: imatha kuchepetsa serum triglycerides (TG) ndi low density lipoprotein cholesterol (LDL-C), ndipo imatha kukulitsa kuchuluka kwa lipoproteins apamwamba kwambiri mpaka otsika osalimba lipoproteins mwa odwala onenepa kwambiri.
Hebei Guanlang Biotechnology Co., Ltd. ndi ya Guanlang Gulu, yomwe idakhazikitsidwa mu 2007, yomwe ili mumzinda wa Shijiazhuang womwe ndi likulu la Chigawo cha Hebei komanso gawo lapakati pakati pa Beijing Tianjin ndi Hebei ndipo ali ndi mwayi woyendera bwino.Kampani yathu ndi bizinesi yamakono yamankhwala apamwamba kwambiri ndi Research & Development, kupanga ndi sales.Tili ndi fakitale yathu ndi labu, timaperekanso ntchito zopangira makonda kwa makasitomala athu.
